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B. Tech. (Biotechnology) Entrance Exam

Model Question Paper 

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Unit-I: Reproduction

Ch-1: Sexual Reproduction in Flowering Plants

  • Flower structure

  • Development of male and female gametophytes

  • Pollination: Types, agencies, and examples

  • Outbreeding devices

  • Pollen-pistil interaction

  • Double fertilization

  • Post-fertilization events:

    • Development of endosperm and embryo

    • Development of seed and formation of fruit

  • Special modes:

    • Apomixis

    • Parthenocarpy

    • Polyembryony

  • Significance of seed dispersal and fruit formation

Chapter-2: Human Reproduction

  • Male and female reproductive systems

  • Microscopic anatomy of testis and ovary

  • Gametogenesis:

    • Spermatogenesis

    • Oogenesis

  • Menstrual cycle

  • Fertilization and embryo development up to blastocyst formation

  • Implantation

  • Pregnancy and placenta formation (elementary idea)

  • Parturition (elementary idea)

  • Lactation (elementary idea)

Chapter-3: Reproductive Health

  • Need for reproductive health

  • Prevention of Sexually Transmitted Diseases (STDs)

  • Birth control:

    • Need and methods

    • Contraception and medical termination of pregnancy (MTP)

  • Amniocentesis

  • Infertility and assisted reproductive technologies:

    • IVF

    • ZIFT

    • GIFT (elementary idea for general awareness)

Unit-II: Genetics and Evolution

Chapter-4: Principles of Inheritance and Variation

  • Heredity and variation

  • Mendelian inheritance

  • Deviations from Mendelism:

    • Incomplete dominance

    • Co-dominance

    • Multiple alleles and inheritance of blood groups

    • Pleiotropy

    • Elementary idea of polygenic inheritance

  • Chromosome theory of inheritance

  • Chromosomes and genes

  • Sex determination in humans, birds, and honey bee

  • Linkage and crossing over

  • Sex-linked inheritance:

    • Haemophilia

    • Colour blindness

  • Mendelian disorders in humans:

    • Thalassemia

  • Chromosomal disorders in humans:

    • Down's syndrome

    • Turner's syndrome

    • Klinefelter's syndrome

Chapter-5: Molecular Basis of Inheritance

  • Search for genetic material and DNA as genetic material

  • Structure of DNA and RNA

  • DNA packaging

  • DNA replication

  • Central Dogma

  • Transcription

  • Genetic code

  • Translation

  • Gene expression and regulation: Lac operon

  • Genome projects:

    • Human genome project

    • Rice genome project

  • DNA fingerprinting

Chapter-6: Evolution

  • Origin of life

  • Biological evolution and evidences:

    • Paleontology

    • Comparative anatomy

    • Embryology

    • Molecular evidences

  • Darwin's contribution

  • Modern synthetic theory of evolution

  • Mechanism of evolution:

    • Variation (mutation and recombination)

    • Natural selection (with examples)

    • Types of natural selection

  • Gene flow and genetic drift

  • Hardy-Weinberg's principle

  • Adaptive radiation

  • Human evolution

Unit-III: Biology and Human Welfare

Chapter-7: Human Health and Disease

  • Pathogens and parasites causing human diseases:

    • Malaria

    • Dengue

    • Chikungunya

    • Filariasis

    • Ascariasis

    • Typhoid

    • Pneumonia

    • Common cold

    • Amoebiasis

    • Ringworm

  • Control measures

  • Basic concepts of immunology: Vaccines

  • Cancer

  • HIV and AIDS

  • Adolescence: Drug and alcohol abuse

Chapter-8: Microbes in Human Welfare

  • Microbes in:

    • Food processing

    • Industrial production

    • Sewage treatment

    • Energy generation

    • Biocontrol agents

    • Bio-fertilizers

  • Antibiotics: Production and judicious use

Unit-IV: Biotechnology and its Applications

Chapter-9: Biotechnology: Principles and Processes

  • Genetic Engineering (Recombinant DNA Technology)

Chapter-10: Biotechnology and its Applications

  • Applications in health and agriculture:

    • Human insulin and vaccine production

    • Stem cell technology

    • Gene therapy

  • Genetically modified organisms:

    • Bt crops

    • Transgenic animals

  • Biosafety issues

  • Biopiracy and patents

Unit-V: Ecology and Environment

Chapter-11: Organisms and Populations

  • Population interactions:

    • Mutualism

    • Competition

    • Predation

    • Parasitism

  • Population attributes:

    • Growth

    • Birth rate

    • Death rate

    • Age distribution

(Topics excluded: Organism and its Environment, Major Abiotic Factors, Responses to Abiotic Factors, Adaptations)

Chapter-12: Ecosystem

  • Ecosystems:

    • Patterns

    • Components

    • Productivity and decomposition

    • Energy flow

    • Pyramids of number, biomass, and energy

(Topics excluded: Ecological Succession and Nutrient Cycles)

Chapter-13: Biodiversity and Conservation

  • Biodiversity:

    • Concept

    • Patterns

    • Importance

  • Loss of biodiversity

  • Biodiversity conservation:

    • Hotspots

    • Endangered organisms

    • Extinction

    • Red Data Book

    • Sacred Groves

    • Biosphere reserves

    • National parks

    • Wildlife sanctuaries

    • Ramsar sites

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